Preliminary study of cytogenetic damage in personnel exposed to anesthetic gases
نویسندگان
چکیده
منابع مشابه
Cytogenetic Damage in Operating Room Nurses Exposed to Anesthetic Gases
Background: Although eliminated rapidly from the body due to low solubility in blood and tissues, anesthetic gases have been reported to be neurotoxic, teratogenic and carcinogenic. Genetic material has been shown to be a sensitive target of numerous harmful agents. Aim of the Work: To evaluate genotoxic risk of occupational exposure to anesthetic gases in a group of operating room nurses. Subj...
متن کاملAssessment of adaptive response of gamma radiation in the operating room personnel exposed to anesthetic gases by measuring the expression of Ku 80, Ligase1 and P53 genes
Introduction: Staffs of operating room are continuously exposed to anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA that causes in the next exposures to higher doses o...
متن کاملEvaluation of cytogenetic damage in nuclear medicine personnel occupationally exposed to low-level ionising radiation.
The aim of this study was to provide data on genetic hazards associated with occupational exposure to low doses of ionising radiation in nuclear medicine departments. The DNA damage in peripheral blood lymphocytes of medical staff was assessed using the chromosome aberration test. Altogether 120 subjects (60 exposed and 60 controls) participated in the study. The exposed subjects showed signifi...
متن کاملAssessment of Adaptive Response of Gamma Radiation in the Operating Room Personnel Exposed to Anesthetic Gases by Measuring the Relative Gene Expression Changes Ku80, Ligase1 and P53
Background: Some operating room personnel are occupationally exposed to genotoxic agents such as anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA (priming dose), which in the subsequent exposure to higher dose of those factors (challenging dose), show more resistance and sensibility.. <b...
متن کاملEvaluation of genetic damage in operating room personnel exposed to anaesthetic gases.
Information on potential genetic damage in humans after exposure to waste anaesthetic gases in Indian hospitals is scarce. To evaluate the possible genotoxic effects of waste anaesthetic gases, the chromosomal aberrations analysis and comet assay were studied in peripheral blood lymphocytes in 45 operating room personnel currently employed at a hospital in South India. In addition, the micronuc...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2001
ISSN: 1464-3804
DOI: 10.1093/mutage/16.2.139